Anti-VEGF (A.4.6.1)

Anti-VEGF [A.4.6.1], Recombinant, IgG1 kappa, Mouse

CloneID: A.4.6.1

Antigen Long Description: Recombinant human VEGF.

Origin Pub PMID: 9377574

Buffer Composition: PBS only.

Uniprot Accession No.: P15692

Specificity Statement: Binds native and reduced human VEGF (isoform 165), with a Kd of 0.8 nm determined for the original clone.

Application Notes (Clone): This is the parental antibody clone to the humanized, therapeutic antibody Bevacizumab (marketed as Avastin) binding to VEGF. VEGF is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.

• SKU: ABAAb00339-1.1-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00339-1.1-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human, Rat (Rattus)
• Clonality: Recombinant
• Application: Immunoprecipitation, Western Blotting, ELISA, Flow Cytometry, Immunohistochemistry
• Isotype: IgG1 kappa
• Host: Mouse