Apalutamide, CAS 956104-40-8

Product Description: Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1].

Applications: Cancer-programmed cell death

Formula: C21H15F4N5O2S

References: [1]Clegg NJ, et al. ARN-509: a novel antiandrogen for prostate cancer treatment. Cancer Res. 2012 Mar 15;72(6):1494-503./[2]Smith MR, et al. Phase 2 Study of the Safety and Antitumor Activity of Apalutamide (ARN-509), a Potent Androgen Receptor Antagonist, in the High-risk Nonmetastatic Castration-resistant Prostate Cancer Cohort. Eur Urol. 2016 May 6. pii: S0302-2838(16)30133

CAS Number: 956104-40-8

Molecular Weight: 477.43

Compound Purity: 99.93

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Androgen Receptor

• SKU: MEXHY-16060-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-16060-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK