APC Anti-Human CD101 Antibody(BB27)

Target Synonym: P126;V7

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Citation Link 1: https://789.bio/ec/GWfjnP

Citation Link 2: Human peripheral blood lymphocytes are stained with FITC Anti-Human CD3 Antibody and APC Anti-Human CD101 Antibody[BB27] (Left). Lymphocytes are stained with FITC Anti-Human CD3 Antibody and APC Mouse IgG1, κ Isotype Control (Right).

Background: CD101 is a type I transmembrane glycoprotein, known as V7, and P126. It is a 120 kD homodimer, the member of EWI family within Ig superfamily. CD101 is found on monocytes, granulocytes, dendritic cells, a subpopulation of peripheral blood T cells and activated T cells. It has been reported that CD101 expressing Tregs posses higher inhibitory function. The biological function of CD101 is still not clear. But it has been found that BB27 antibody is able to inhibit T cell proliferative responses and this inhibitory function can be overcome by high doses of IL-2. Activation of CD101 on dendritic cells is able to induce IL-10 production.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• SKU: ELSE-AB-F1361E-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F1361E-100
• Package Unit: 100 Tests
• Quantity Unit: PAK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Mouse IgG1 κ
• Host: Mouse
• Conjugate: Conjugated, APC (Allophycocyanin)