APC Anti-Mouse CD49b/pan-NK cells Antibody(DX5)

Target Synonym: CD49 antigen-like family member B;CD49b;Collagen receptor;GPIa;Integrin alpha-2;Platelet membrane glycoprotein Ia;VLA-2 subunit alpha

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation Link 1: https://789.bio/ec/fHKOS4

Citation Link 2: C57BL/6 murine splenocytes are stained with FITC Anti-Mouse CD161/NK1.1 Antibody and APC Anti-Mouse CD49b Antibody (Left). Splenocytes are stained with FITC Anti-Mouse CD161/NK1.1 Antibody and APC Rat IgM, κ Isotype Control (Right).

Background: DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• SKU: ELSE-AB-F1116E-2X100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F1116E-2X100
• Package Unit: 100 Testsx2
• Quantity Unit: PAK
• Reactivity: Mouse (Murine)
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Rat IgM κ
• Human Gene ID: 16398
• Host: Rat
• Conjugate: Conjugated, APC (Allophycocyanin)