APC Anti-Rat CD161 Antibody(3.2.3)

Target Synonym: CD161a/CD161bNKR-P1a/KLRB1a;NKR-P1

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation Link 1: https://789.bio/ec/zDOOO0

Citation Link 2: Rat splenocytes are stained with FITC Anti-Rat CD3 Antibody and APC Anti-Rat CD161 Antibody (Left). Splenocytes are stained with FITC Anti-Rat CD3 Antibody and APC Mouse IgG1, κ Isotype Control (Right).

Background: CD161 is a 30 kD type II transmembrane C-type lectin, expressed as a homodimer. Rat NKR-P1 receptors are primarily expressed on NK cells, a subset of T cells, dendritic cells, and activated monocytes. There are three different types of NKR-P in rat, namely NKR-P1a, NKR-P1b, and NKR-P1c. NKR-P1a does not contain an ITIM structure and is an activating receptor, while NKR-P1b contains an ITIM and displays inhibitory function. LLT-1 (ligand lectin like transcript 1) is the ligand, while KLR (killer cell lectin like) functions as a receptor.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• SKU: ELSE-AB-F1307E-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F1307E-100
• Package Unit: 100 Tests
• Quantity Unit: PAK
• Reactivity: Rat (Rattus)
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Mouse IgG1 κ
• Human Gene ID: 362443
• Host: Mouse
• Conjugate: Conjugated, APC (Allophycocyanin)