APG-1387, CAS 1570231-89-8

Description: APG-1387 (SM-1387) is an IAP inhibitor that promotes the rapid degradation of cIAP1/2 and XIAP and exerts an anti-tumor effect on nasopharyngeal carcinoma stem cells. Studies have shown that APG-1387 combined with NPC's CDDP and 5-FU enhance chemoresensitivity and promote cell apoptosis in vitro and in vivo.

CAS Number: 1570231-89-8

Formula: C60H72N10O10S2

Molecular Weight: 1157,41

References: Rzymski T, Mikula M, Żyłkiewicz E,et al. SEL120-34A is a novel CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domains. Oncotarget. 2017 May 16;8(20):33779-33795. doi: 10.18632/oncotarget.16810. PubMed PMID: 28422713; PubMed Central PMCID: PMC5464911.

• SKU: TGMT30095-10mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T30095-10mg
• Package Unit: 10 mg
• Quantity Unit: STK