Apicularen B, CAS 220757-06-2

Product Description: Apicularen B is a V-ATPase inhibitor and cytotoxic macrolide that can be obtained from the myxobacterium Archangium gephyra. Apicularen B can be used in the study of V-ATPase-related diseases, such as osteopetrosis[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C33H44N2O11

References: [1]Köteles I, et al. Synthesis of Potential Haptens with Morphine Skeleton and Determination of Protonation Constants. Molecules. 2020 Sep 2;25(17):4009./[2]Hong J, et al. Inhibition of vacuolar-type (H+)-ATPase by the cytostatic macrolide apicularen A and its role in apicularen A-induced apoptosis in RAW 264.7 cells. FEBS Lett. 2006 May 15;580(11):2723-30.

CAS Number: 220757-06-2

Molecular Weight: 644.71

Research Area: Others

Solubility: 10 mM in DMSO

Target: Proton Pump

• SKU: MEXHY-N12413-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N12413-0
• Package Unit: Get quote
• Quantity Unit: STK