Product Description: Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM.
Applications: COVID-19-immunoregulation
Formula: C15H10O5
References: [1]Si D, et al. Mechanism of CYP2C9 inhibition by flavones and flavonols. Drug Metab Dispos. 2009 Mar;37(3):629-34./[2]Wu K, et al. Inhibitory effects of apigenin on the growth of gastric carcinoma SGC-7901 cells. World J Gastroenterol. 2005 Aug 7;11(29):4461-4./[3]Yu W, et al. Apigenin Attenuates Adriamycin-Induced Cardiomyocyte Apoptosis via the PI3K/AKT/mTOR Pathway. Evid Based Complement Alternat Med. 2017;2017:2590676.
CAS Number: 520-36-5
Molecular Weight: 270.24
Compound Purity: 99.58
Research Area: Inflammation/Immunology; Cancer
Solubility: DMSO : 83.33 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL
Target: Autophagy;Cytochrome P450;Endogenous Metabolite
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