Product Description: Arg-Gly-Asp (RGD) is a synthetic peptide corresponding to the cell adhesion sequence for the integrins αVβ1, αVβ3, αVβ5, αVβ6, αVβ8, α8β1, and α5β1. It is a component of radioligands and peptidomimetics that have been used in the study of integrin expression and activity in vivo.
Applications: Cancer-programmed cell death
Formula: C14H23F3N6O8
References: [1]Ruoslahti, et al. RGD and other recognition sequences for integrins. Annu. Rev. Cell Dev. Biol. 12, 697-715 (1996).
CAS Number: 120103-89-1
Molecular Weight: 460.36
Research Area: cancer
Target: Integrin