ARM1, CAS 68729-05-5

ARM1, CAS 68729-05-5
SKU
CAY15865-100
Packaging Unit
100 mg
Manufacturer
Cayman Chemical

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Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-[4-(phenylmethyl)phenyl]-2-thiazolamine

Purity: ≥95%

Formula Markup: C16H16N2S

Formula Weight: 268.4

CAS Number: 68729-05-5

Notes: Leukotriene A4 (LTA4) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB4 (Item No. 20110) from LTA4 and cleaves the chemotactic peptide Pro-Gly-Pro.{12673,20329} ARM1 is a thiazolamine that inhibits LTB4 synthesis in human neutrophils (IC50 = ~0.5 µM) and conversion of LTA4 to LTB4 by purified LTA4 hydrolase (Ki = 2.3 µM).{25663} ARM1 does not significantly affect the hydrolysis of Pro-Gly-Pro by LTA4 hydrolase.{25663}
More Information
SKU CAY15865-100
Manufacturer Cayman Chemical
Manufacturer SKU 15865-100
Package Unit 100 mg
Quantity Unit STK
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