Product Description: ARN14974, a benzoxazolone carboxamide, is a potent and systemically active inhibitors of intracellular acid ceramidase (IC50=79 nM)[1].
Applications: Cancer-programmed cell death
Formula: C24H21FN2O3
References: [1]Pizzirani D, et al. Benzoxazolone carboxamides: potent and systemically active inhibitors of intracellular acid ceramidase. Angew Chem Int Ed Engl. 2015;54(2):485-489.
CAS Number: 1644158-57-5
Molecular Weight: 404.43
Compound Purity: 99.29
Research Area: Cancer
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)