Product Description: Asperosaponin VI (Standard) is the analytical standard of Asperosaponin VI. This product is intended for research and analytical applications. Asperosaponin VI is a saponin component from Dipsacus asper. Asperosaponin VI induces osteoblast differentiation through the BMP-2/p38 and ERK1/2 signaling pathways. Asperosaponin VI protects against hypoxia-induced cardiomyocyte apoptosis by activating the PI3K/Akt and CREB pathways. Additionally, Asperosaponin VI also has antidepressant and wound-healing-promoting activities[1][2].
Formula: C47H76O18
References: [1]Niu Y, et al. Asperosaponin VI, a saponin component from <i>Dipsacus asper</i> wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway. Phytother Res. 2011 Nov;25(11):1700-6./[2]Li C, et al. Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways. Eur J Pharmacol. 2010 Dec 15;649(1-3):100-7.
CAS Number: 39524-08-8
Molecular Weight: 929.10
Research Area: Neurological Disease; Cardiovascular Disease
Target: Akt;Apoptosis;Caspase;HIF/HIF Prolyl-Hydroxylase;p38 MAPK;PERK;PPAR;Reference Standards
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