AT7867, CAS 857531-00-1

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-(4-chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]-piperidine

Purity: ≥98%

Formula Markup: C20H20ClN3

Formula Weight: 337.9

CAS Number: 857531-00-1

Notes: AT7867 is a potent and orally bioavailable inhibitor of Akt isoforms Akt1, 2, and 3 (IC50s = 32, 17, and 47 nM, respectively).{33635} It also inhibits p70S6 kinase and PKA (IC50s = 85 and 20 nM, respectively), but is without effect against a panel of other kinases.{33635} AT7867 inhibits growth and induces apoptosis in a variety of cancer cell lines in vitro and suppresses tumor growth of PTEN-deficient xenografts in mice.{33635}

• SKU: CAY16848-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 16848-25
• Package Unit: 25 mg
• Quantity Unit: STK