ATH686, CAS 853299-52-2

Product Description: ATH686 is a potent, selective and ATP-competitive FLT3 inhibitor. ATH686 target mutant FLT3 protein kinase activity and inhibit the proliferation of cells harboring FLT3 mutants via induction of apoptosis and cell cycle inhibition. ATH686 has antileukemic effects[1].

Applications: Cancer-Kinase/protease

Formula: C25H28F3N7O2

References: [1]Ellen Weisberg, et al. Antileukemic Effects of Novel First- and Second-Generation FLT3 Inhibitors: Structure-Affinity Comparison. Genes Cancer. 2010 Oct;1(10):1021-32.

CAS Number: 853299-52-2

Molecular Weight: 515.53

Compound Purity: 99.38

Research Area: Cancer

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: Apoptosis;FLT3

• SKU: MEXHY-15003-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15003-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK