AZ 505, CAS 1035227-43-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-cyclohexyl-3-[[2-(3,4-dichlorophenyl)ethyl]amino]-N-[2-[[2-(3,4-dihydro-5-hydroxy-3-oxo-2H-1,4-benzoxazin-8-yl)ethyl]amino]ethyl]-propanamide

Purity: ≥95%

Formula Markup: C29H38Cl2N4O4

Formula Weight: 577.6

CAS Number: 1035227-43-0

Notes: AZ 505 is an inhibitor of the lysine N-methyltransferase SMYD2 (IC50 = 0.12 μM).{27559} It is selective for SMYD2 over SMYD3, DOT1L, EZH2, GLP, G9A, and SET7/9 (IC50s = >83.3 μM). AZ 505 (10 mg/kg) delays cyst growth in early- and late-stage Pdk1 conditional knockout mouse models of polycystic kidney disease.{48014}

• SKU: CAY16875-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 16875-5
• Package Unit: 5 mg
• Quantity Unit: STK