AZD-7762, CAS 860352-01-8

Product Description: AZD-7762 is a potent ATP-competitive checkpoint kinase (Chk) inhibitor in with an IC50 of 5 nM for Chk1.

Applications: Cancer-Kinase/protease

Formula: C17H19FN4O2S

References: [1]Zabludoff SD, et al. AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies. Mol Cancer Ther. 2008 Sep;7(9):2955-66./[2]Quin J, et al. Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling. Oncotarget. 2016 Aug 2;7(31):49800-49818.

CAS Number: 860352-01-8

Molecular Weight: 362.4217632

Compound Purity: 99.95

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Checkpoint Kinase (Chk)

• SKU: MEXHY-10992-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10992-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK