AZD4320, CAS 1357576-48-7

Product Description: AZD4320 is a novel BH3-mimicking dual BCL2/BCLxL inhibitor with IC50s of 26 nM, 17 nM, and 170 nM for KPUM-MS3, KPUM-UH1, and STR-428 cells, respectively.

Applications: Cancer-programmed cell death

Formula: C45H48ClF3N4O7S3

References: [1]Takimoto-Shimomura T, et al. Dual targeting of bromodomain-containing 4 by AZD5153 and BCL2 by AZD4320 against B-cell lymphomas concomitantly overexpressing c-MYC and BCL2. Invest New Drugs. 2018 Jun 21.

CAS Number: 1357576-48-7

Molecular Weight: 945.53

Compound Purity: 99.68

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Bcl-2 Family

• SKU: MEXHY-112416-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-112416-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK