Product Description: AZD5423 is an inhaled, potent, selective, and non-steroidal glucocorticoid receptor (GR) modulator (SGRM)[1]. AZD5423 effectively reduces allergen-induced responses in subjects with mild allergic asthma[2].
Applications: COVID-19-immunoregulation
Formula: C25H21F4N3O3
References: [1]Werkström V, et al. Safety, Pharmacokinetics and Pharmacodynamics of the Selective Glucocorticoid Receptor Modulator AZD5423 after Inhalation in Healthy Volunteers. Basic Clin Pharmacol Toxicol. 2016 Dec;119(6):574-581./[2]Gauvreau GM, et al. A nonsteroidal glucocorticoid receptor agonist inhibits allergen-induced late asthmatic responses. Am J Respir Crit Care Med. 2015 Jan 15;191(2):161-7.
CAS Number: 1034148-04-3
Molecular Weight: 487.45
Compound Purity: 99.85
Research Area: Inflammation/Immunology; Endocrinology
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Glucocorticoid Receptor
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