AZD8329, CAS 1048668-70-7

Product Description: AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1, displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C25H31N3O3

References: [1]Scott JS, et al. Novel acidic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with reduced acyl glucuronide liability: the discovery of 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid (AZD8329). J Med Chem. 2012 Nov 26;55(22):10136-47.

CAS Number: 1048668-70-7

Molecular Weight: 421.53

Compound Purity: 99.74

Research Area: Metabolic Disease

Solubility: DMSO : 62.5 mg/mL (ultrasonic)

Target: 11β-HSD

• SKU: MEXHY-18173-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-18173-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK