Product Description: β-Glycerophosphate disodium salt pentahydrate is a bioactive endogenous metabolite and a phosphatase inhibitor. β-Glycerophosphate disodium salt pentahydrate plays an important role in inducing and maintaining osteoblast differentiation, mineral metabolism and signal transduction, and can be used as a drug carrier to form heat-sensitive hydrogels. β-Glycerophosphate disodium salt hydrate accelerates the calcification of vascular smooth muscle cells[1][2][3].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C3H7O6PNa2.xH2O
Citations: Adv Mater. 2024 Dec 26:e2415543./IUBMB Life. 2024 Jul 16./J Dent Sci. 6 December 2021./J Pharm Anal. 2024 Oct 2./Redox Rep. 2024 Dec;29(1):2428147./Research Square Print. 2022 Aug./Biomaterials. 2024 Aug 15:313:122756./J Ethnopharmacol. 2024 Nov 29:340:119128./J Mol Histol. 2021 Oct;52(5):1067-1080./J Mol Histol. 2024 May 27./Mater Today Bio. 2023 Jun, 20, 100667.
References: [1]Belfield A, et al. Inhibition of the nucleotidase effect of alkaline phosphatase by beta-glycerophosphate. Nature. 1968 Jul 6;219(5149):73-5./[2]Shioi A, et al. Beta-glycerophosphate accelerates calcification in cultured bovine vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 1995 Nov;15(11):2003-9./[3]Langenbach F, et al. Effects of dexamethasone, ascorbic acid and β-glycerophosphate on the osteogenic differentiation of stem cells in vitro. Stem Cell Res Ther. 2013;4(5):117.
CAS Number: 154804-51-0
Molecular Weight: N/A
Compound Purity: 98.0
Research Area: Metabolic Disease
Solubility: H2O : 250 mg/mL (ultrasonic)
Target: Endogenous Metabolite;ERK;Phosphatase
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