Description: B-Raf IN 11 is a novel selective inhibitor. The DFG-in conformation of the B-Raf kinase V600E mutant is superior to the DFG-out conformation in colorectal cancer.
CAS Number: 918504-27-5
Formula: C17H14BrF2N3O3S
Molecular Weight: 458,28
References: Andrew P. CrewKeith R. Hornberger, et al. Polycyclic compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides. WO2020051564A1