Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: (1S,2R,4aR,6aS,6bR,8aR,10S,12aR,12bR,14aR,14bS)-hexadecahydro-1-hydroxy-1,6b,9,9,12a-pentamethyl-2-(2-methyl-1-propen-1-yl)-4a,6a-methano-1H,6H-phenanthro[2,1-d]pyrano[2,3-b]pyran-10-yl O-a-L-arabinofuranosyl-(1?2)-O-[ß-D-glucopyranosyl-(1?3)]-a-L-arabinopyranoside
Purity: ≥95%
Formula Markup: C46H74O17
Formula Weight: 899.1
CAS Number: 178064-13-6
Notes: Bacopasaponin C is a triterpenoid saponin originally isolated from B. monniera that has diverse biological activities.{48521,48522,48523} It inhibits the ATPase activity of P-glycoprotein (IC50 = 57.83 µg/ml).{39064} Bacopasaponin C inhibits scopolamine-induced impairments in spatial memory in the Morris water maze and memory retrieval in the step-down test in mice when administered at a dose of 50 mg/kg.{48521} It also decreases the time mice spent immobile in the forced swim and tail suspension tests, indicating antidepressant-like activity.{48522} Bacopasaponin C reduces the spleen parasite load in a hamster model of leishmaniasis when administered as a free compound or in liposomal, niosomal, microencapsulated, or nanocapsulated forms.{48523}
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