Product Description: Balovaptan (RG7314) is an orally available, selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors, and is used for the research of autism.
Applications: Neuroscience-Neuromodulation
Formula: C22H24ClN5O
References: [1]Ratni H, et al. Discovery of highly selective brain-penetrant vasopressin 1a antagonists for the potential treatment of autism via a chemogenomic and scaffold hopping approach. J Med Chem. 2015 Mar 12;58(5):2275-89.
CAS Number: 1228088-30-9
Molecular Weight: 409.91
Compound Purity: 99.89
Research Area: Neurological Disease; Endocrinology; Cardiovascular Disease
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Vasopressin Receptor