Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: (4S)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-methyl 5-[(3S)-1-(phenylmethyl)-3-pyrrolidinyl] ester, monohydrochloride
Purity: ≥98%
Formula Markup: C27H29N3O6 / HCl
Formula Weight: 528.0
CAS Number: 104757-53-1
Notes: Barnidipine is a dihydropyridine calcium channel blocker that has an IC50 value of 0.35 nM in potassium-induced tonic contraction of pig coronary artery.{34407} It demonstrates antihypertensive activity by reducing peripheral vascular resistance. It decreases blood pressure in spontaneously hypertensive rats when administered orally at 1 and 3 mg/kg per day.{34406} Formulations containing barnidipine have been used as a treatment for hypertension.