Basmisanil, CAS 1159600-41-5

Product Description: Basmisanil (RG1662) is a highly selective orally active α subunit-containing GABAA receptors (GABAAα5) negative allosteric modulator (NAMs). Basmisanil can inhibit GABAA-α5 with a Ki value of 5 nM and IC50 value of 8 nM, respectively. Basmisanil can be used for the research of multiple cognitive and psychiatric disorders[1].

Applications: Neuroscience-Neuromodulation

Formula: C21H20FN3O5S

References: [1]Joerg F Hipp, et al. Basmisanil, a highly selective GABA A-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man. Sci Rep. 2021 Apr 8;11(1):7700.

CAS Number: 1159600-41-5

Molecular Weight: 445.46

Compound Purity: 99.91

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: GABA Receptor

• SKU: MEXHY-16716-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-16716-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK