Product Description: Batabulin (T138067) is an antitumor agent, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization. Batabulin affects cell morphology and leads to cell-cycle arrest ultimately induces apoptotic cell death[1].
Applications: Cancer-programmed cell death
Formula: C13H7F6NO3S
References: [1]Shan B, et al. Selective, covalent modification of beta-tubulin residue Cys-239 by T138067, an antitumor agent with in vivo efficacy against multidrug-resistant tumors. Proc Natl Acad Sci U S A. 1999 May 11;96(10):5686-91.
CAS Number: 195533-53-0
Molecular Weight: 371.26
Compound Purity: 99.89
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)/Ethanol : 100 mg/mL (ultrasonic)
Target: Apoptosis;Microtubule/Tubulin