Bavdegalutamide, CAS 2222112-77-6

Product Description: Bavdegalutamide (ARV-110) is an orally active, specific androgen receptor (AR) PROTAC degrader. Bavdegalutamide promotes ubiquitination and degradation of AR. Bavdegalutamide can be used for the research of prostate cancer (Pink: AR ligand (HY-168299); Blue: E3 ligase ligand (HY-W093272); Black: linker (HY-W091986))[1].

Applications: Cancer-programmed cell death

Formula: C41H43ClFN9O6

References: [1]Taavi Neklesa, et al. ARV-110: An androgen receptor PROTAC degrader for prostate cancer. American Association for Cancer Research. 2018. 78 (13): pp. 5236./[2]Taavi K Neklesa,et al. ARV-110: an oral androgen receptor PROTAC degrader for prostate cancer. GU ASCO 2019

CAS Number: 2222112-77-6

Molecular Weight: 812.29

Compound Purity: 99.64

Research Area: Cancer

Solubility: DMSO : 26.67 mg/mL (ultrasonic;warming;adjust pH to 3 with HCl;heat to 80°C)

Target: Androgen Receptor;PROTACs

• SKU: MEXHY-138641-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-138641-100
• Package Unit: 100 mg
• Quantity Unit: STK