BAY 11-7085, CAS 196309-76-9

Product Description: BAY 11-7085 (BAY 11-7083) is an inhibitor of NF-κB activation and phosphorylation of IκBα; it stabilizes IκBα with an IC50 of 10 μM[1].

Applications: Cancer-Kinase/protease

Formula: C13H15NO2S

References: [1]Pierce JW, et al. Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesionmolecule expression show anti-inflammatory effects in vivo. J Biol Chem. 1997 Aug 22;272(34):21096-103./[2]Nasu K, et al. Application of the nuclear factor-kappaB inhibitor BAY 11-7085 for the treatment of endometriosis: an in vitro study. Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E16-23.

CAS Number: 196309-76-9

Molecular Weight: 249.33

Compound Purity: 99.99

Research Area: Cancer

Solubility: DMSO : ≥ 26 mg/mL/H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Apoptosis;Ferroptosis;NF-κB

• SKU: MEXHY-10257-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10257-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK