BAY 60-6583, CAS 910487-58-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide

Purity: ≥98%

Formula Markup: C19H17N5O2S

Formula Weight: 379.4

CAS Number: 910487-58-0

Notes: BAY 60-6583 is an adenosine A2B receptor agonist (EC50 = 3 nM for human A2B receptors) that displays selectivity over A1, A2A, and A3 receptors (EC50s = >10 µM).{27932} It has been used to decrease superoxide production in neutrophils and to study the role of the A2B receptor in regulating inflammation and mediating metabolic homeostasis in a mouse model of type 2 diabetes and obesity.{27933,27934} BAY 60-6583 has also been examined for potential clinical use in disorders of the coronary arteries and atherosclerosis and in ischemia-reperfusion injury.{27932}

• SKU: CAY17127-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 17127-5
• Package Unit: 5 mg
• Quantity Unit: STK