Product Description: BAY-85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE), with an IC50 of 65 pM.
Applications: Metabolism-protein/nucleotide metabolism
Formula: C22H17F3N4O3S
References: [1]Von Nussbaum F, et al. Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases. ChemMedChem. 2015 Jul;10(7):1163-73.
CAS Number: 1161921-82-9
Molecular Weight: 474.46
Compound Purity: 99.72
Research Area: Metabolic Disease
Solubility: DMSO : 200 mg/mL (ultrasonic)
Target: Elastase