Product Description: BAY 87-2243 is a highly potent and selective hypoxia-inducible factor-1 (HIF-1) inhibitor.
Applications: Cancer-programmed cell death
Formula: C26H26F3N7O2
References: [1]Ellinghaus P, et al. BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I. Cancer Med. 2013 Oct;2(5):611-24./[2]Helbig L, et al. BAY 87-2243, a novel inhibitor of hypoxia-induced gene activation, improves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenografts. Radiat Oncol. 2014 Sep 19;9:207.
CAS Number: 1227158-85-1
Molecular Weight: 525.53
Compound Purity: 99.41
Research Area: Cancer
Solubility: DMSO : 25 mg/mL (ultrasonic)
Target: Ferroptosis;HIF/HIF Prolyl-Hydroxylase