BDTX-189, CAS 2414572-47-5

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-[4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-7-[2-(4-morpholinyl)ethoxy]-6-quinazolinyl]-2-propenamide

Purity: ≥98%

Formula Markup: C29H29ClN6O4

Formula Weight: 561.0313

CAS Number: 2414572-47-5

Notes: BDTX-189 is an inhibitor of wild-type and mutant EGFR and HER2 (IC50s = ≤30-500 and ≤10-100 nM, respectively).{62202} In vivo, BDTX-189 (30 and 50 mg/kg, twice daily) reduces tumor growth in a CUTO14 non-small cell lung cancer (NSCLC) mouse xenograft model.

• SKU: CAY33932-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 33932-1
• Package Unit: 1 mg
• Quantity Unit: STK