Product Description: Belotecan hydrochloride (CKD-602 hydrochloride), a Topoisomerase I inhibitor, is a synthetic camptothecin derivative.
Applications: Cancer-programmed cell death
Formula: C25H28ClN3O4
References: [1]Kim YK, et al. Anticancer effects of CKD-602 (Camtobell?) via G2/M phase arrest in oral squamous cell carcinoma cell lines. Oncol Lett. 2015 Jan;9(1):136-142./[2]Kim YY, et al. CKD-602, a camptothecin derivative, inhibits proliferation and induces apoptosis in glioma cell lines. Oncol Rep. 2009 Jun;21(6):1413-9./[3]Kim CY, et al. Antitumor activity of CKD-602, a camptothecin derivative, in a mouse glioma model. J Clin Neurosci. 2012 Feb;19(2):301-5.
CAS Number: 213819-48-8
Molecular Weight: 469.96
Compound Purity: 99.88
Research Area: Cancer
Solubility: DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Topoisomerase