Bengamide B, CAS 104947-69-5

Product Description: Bengamide B is an inhibitor for NF-κB with an IC50 of 85 nM. Bengamide B inhibits LPS (HY-D1056)-induced expression of TNF-α, IL-6 and MCP-1, exhibits anti-inflammatory activity. Bengamide B exhibits antitumor efficacy (IC50 for HCT-116 is 2 nM)[1].

Formula: C32H58N2O8

References: [1]Johnson TA, et al., Myxobacteria versus sponge-derived alkaloids: the bengamide family identified as potent immune modulating agents by scrutiny of LC-MS/ELSD libraries. Bioorg Med Chem. 2012 Jul 15;20(14):4348-55.

CAS Number: 104947-69-5

Molecular Weight: 598.81

Research Area: Cancer

Target: Interleukin Related;NF-κB

• SKU: MEXHY-110151-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-110151-0
• Package Unit: Get quote
• Quantity Unit: STK