Product Description: Bentamapimod (AS 602801) is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively.
Applications: Cancer-Kinase/protease
Formula: C25H23N5O2S
References: [1]Messoussi A, et al. Recent progress in the design, study, and development of c-Jun N-terminal kinase inhibitors as anticanceragents. Chem Biol. 2014 Nov 20;21(11):1433-43./[2]Okada M, et al. The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo. Oncotarget. 2016 May 10;7(19):27021-32./[3]Palmer SS, et al. Bentamapimod (JNK Inhibitor AS602801) Induces Regression of Endometriotic Lesions in Animal Models. Reprod Sci. 2016 Jan;23(1):11-23.
CAS Number: 848344-36-5
Molecular Weight: 457.55
Compound Purity: 99.32
Research Area: Cancer
Solubility: DMSO : 8.33 mg/mL (ultrasonic;warming;heat to 60°C)
Target: JNK
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