Product Description: BETP is an agonist of glucagon-like peptide-1 (GLP-1) receptor, with EC50s of 0.66 and 0.755 μM for human and rat GLP-1 receptor, respectively.
Applications: Metabolism-sugar/lipid metabolism
Formula: C20H17F3N2O2S
References: [1]Sloop KW, et al. Novel small molecule glucagon-like peptide-1 receptor agonist stimulates insulin secretion in rodents and from human islets. Diabetes. 2010 Dec;59(12):3099-107./[2]Willard FS, et al. Small molecule allosteric modulation of the glucagon-like Peptide-1 receptor enhances the insulinotropic effect of oxyntomodulin. Mol Pharmacol. 2012 Dec;82(6):1066-73.
CAS Number: 1371569-69-5
Molecular Weight: 406.42
Compound Purity: 99.35
Research Area: Metabolic Disease
Solubility: DMSO : 25 mg/mL (ultrasonic)
Target: GCGR