Product Description: BIBP3226 TFA is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 TFA displays anxiogenic-like effect[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C29H32F3N5O5
References: [1]Mollereau C, et al. Agonist and antagonist activities on human NPFF(2) receptors of the NPY ligands GR231118 and BIBP3226. Br J Pharmacol. 2001 May;133(1):1-4./[2]Kask A, et al. Anxiogenic-like effect of the neuropeptide Y Y1 receptor antagonist BIBP3226: antagonism with diazepam. Eur J Pharmacol. 1996 Dec 19;317(2-3):R3-4.
CAS Number: 1068148-47-9
Molecular Weight: 587.59
Compound Purity: 99.25
Research Area: Neurological Disease
Solubility: DMSO : ≥ 100 mg/mL
Target: Neuropeptide Y Receptor
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