Product Description: Binodenoson (MRE-0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging[1].
Applications: Neuroscience-Neuromodulation
Formula: C17H25N7O4
References: [1]Sullivan GW, et al. Neutrophil A2A adenosine receptor inhibits inflammation in a rat model of meningitis: synergy with the type IV phosphodiesterase inhibitor, rolipram. J Infect Dis. 1999;180(5):1550-1560./[2]Glover DK, et al. Pharmacological stress thallium scintigraphy with 2-cyclohexylmethylidenehydrazinoadenosine (WRC-0470). A novel, short-acting adenosine A2A receptor agonist. Circulation. 1996;94(7):1726-1732.
CAS Number: 144348-08-3
Molecular Weight: 391.42
Compound Purity: 98.06
Research Area: Cardiovascular Disease
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: Adenosine Receptor
English
Deutsch
