Biotinylated Anti-CDH1 antibody(DMC484); IgG1 Chimeric mAb

Background: This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants; at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats; a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric; breast; colorectal; thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation; invasion; and:or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq; Nov 2015]

Description: Biotinylated Anti-CDH1 antibody(DMC484); IgG1 Chimeric mAb

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Formulation & Reconstitution: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Target: CDH1

Uniprot ID: P12830

Usage: Research use only

Clone ID: DMC484

Purification: Purified from cell culture supernatant by affinity chromatography

Recommended Dilutions: Flow Cyt 1:100

• SKU: DMADMC100484B-10
• Manufacturer: DIMA Biotechnology
• Manufacturer SKU: DMC100484B-10
• Package Unit: 10 µg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Rabbit/Human Fc chimeric IgG1
• Host: Rabbit
• Conjugate: Conjugated, Biotin