CRISPR

CRISPR

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) are segments of short, regularly placed palindromic nucleotide repetitions. CAS (CRISPR-Associated Protein) is a CRISPR-associated nuclease enabling controlled DNA cleavage.

CRISPR/Cas9 systems allow for targeted gene editing. Briefly, aCRISPR/Cas9 complex binds to a specific DNA sequence, cuts it out and replaces the original sequence with a new sequence. Guide RNA (gRNA) helps to navigate the CRISPR/Cas9 complex in order to target only the specific sequence.

CRISPR/Cas9 represents a valuable tool in gene editing and becomes even more popular in therapy, especially of cancer and other disease involving genetic defects (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315587/).

Picture: CRISPR/Cas9 induced DNA double-strand break.

Highlights:

  • Double nickase plasmids
  • CRISPR/dCas9 activation plasmids
  • CRISPR/dCas9 lentiviral activation particles
  • CRISPR/Cas9 plasmids
  • HDR plasmids
  • CRE vector
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  1. AP4A Hydrolase CRISPR Activation Plasmid (r2)
    AP4A Hydrolase CRISPR Activation Plasmid (r2)
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    Sku SACSC-437371-ACT-2
    Manufact. Skusc-437371-ACT-2
    Packaging Unit20 µg
  2. AP4A Hydrolase CRISPR Activation Plasmid (r)
    AP4A Hydrolase CRISPR Activation Plasmid (r)
    Price is loading...
    Sku SACSC-437371-ACT
    Manufact. Skusc-437371-ACT
    Packaging Unit20 µg
  3. AP4A Hydrolase CRISPR/Cas9 KO Plasmid (r)
    AP4A Hydrolase CRISPR/Cas9 KO Plasmid (r)
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    Sku SACSC-437371
    Manufact. Skusc-437371
    Packaging Unit20 µg
  4. Rock-2 CRISPR Activation Plasmid (r2)
    Rock-2 CRISPR Activation Plasmid (r2)
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    Sku SACSC-437370-ACT-2
    Manufact. Skusc-437370-ACT-2
    Packaging Unit20 µg
  5. Rock-2 CRISPR Activation Plasmid (r)
    Rock-2 CRISPR Activation Plasmid (r)
    Price is loading...
    Sku SACSC-437370-ACT
    Manufact. Skusc-437370-ACT
    Packaging Unit20 µg
  6. Rock-2 CRISPR/Cas9 KO Plasmid (r)
    Rock-2 CRISPR/Cas9 KO Plasmid (r)
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    Sku SACSC-437370
    Manufact. Skusc-437370
    Packaging Unit20 µg
  7. MRGX2 CRISPR Activation Plasmid (r2)
    MRGX2 CRISPR Activation Plasmid (r2)
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    Sku SACSC-437369-ACT-2
    Manufact. Skusc-437369-ACT-2
    Packaging Unit20 µg
  8. MRGX2 CRISPR Activation Plasmid (r)
    MRGX2 CRISPR Activation Plasmid (r)
    Price is loading...
    Sku SACSC-437369-ACT
    Manufact. Skusc-437369-ACT
    Packaging Unit20 µg
  9. MRGX2 CRISPR/Cas9 KO Plasmid (r)
    MRGX2 CRISPR/Cas9 KO Plasmid (r)
    Price is loading...
    Sku SACSC-437369
    Manufact. Skusc-437369
    Packaging Unit20 µg
  10. IL-20Rβ CRISPR Activation Plasmid (r2)
    IL-20Rβ CRISPR Activation Plasmid (r2)
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    Sku SACSC-437368-ACT-2
    Manufact. Skusc-437368-ACT-2
    Packaging Unit20 µg
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113927 items

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