Bisindolylmaleimide IV, CAS 119139-23-0

Product Description: Bisindolylmaleimide IV (Arcyriarubin A) is a potent protein kinase C (PKC) inhibitor, with IC50s ranging from 0.1 to 0.55 μM. Bisindolylmaleimide IV also inhibits PKA (IC50=3.1-11.8μM)[1]. Bisindolylmaleimide IV is a potent, selective inhibitor of human cytomegalovirus (HCMV) replication in cell culture with an IC50 of 0.2 μM[2].

Applications: COVID-19-anti-virus

Formula: C20H13N3O2

References: [1]Slater MJ, et al. Indolocarbazoles: potent, selective inhibitors of human cytomegalovirus replication. Bioorg Med Chem. 1999 Jun;7(6):1067-74./[2]Davis PD, et al. Inhibitors of protein kinase C. 1. 2,3-Bisarylmaleimides. J Med Chem. 1992 Jan;35(1):177-84.

CAS Number: 119139-23-0

Molecular Weight: 327.34

Compound Purity: 99.62

Research Area: Infection

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: CMV;PKC

• SKU: MEXHY-108254-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-108254-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK