BML-284, CAS 853220-52-7

Product Description: BML-284 is a potent and cell-permeable Wnt signaling activator. BML-284 induces TCF-dependent transcriptional activity with an EC50?of 700 nM[1].

Applications: Cancer-programmed cell death

Formula: C19H18N4O3

References: [1]Liu J, et al. A small-molecule agonist of the Wnt signaling pathway. Angew Chem Int Ed Engl. 2005 Mar 18;44(13):1987-90./[2]Ying Jiang, et al. Pizotifen inhibits the proliferation and invasion of gastric cancer cells. Exp Ther Med. 2020 Feb;19(2):817-824./[3]Yunlong Meng, et al. Exposure to pyrimethanil induces developmental toxicity and cardiotoxicity in zebrafish. Chemosphere. 2020 Sep;255:126889.

CAS Number: 853220-52-7

Molecular Weight: 350.37

Compound Purity: 99.95

Research Area: Cancer

Solubility: DMSO : ≥ 100 mg/mL

Target: Wnt

• SKU: MEXHY-19987-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-19987-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK