BMP signaling agonist sb4, CAS 100874-08-6

Product Description: BMP signaling agonist sb4 is a potent benzoxazole bone morphogenetic protein 4 (BMP4) signaling agonist with a EC50 value of 74 nM, activates BMP signaling by stabilizing intracellular p-SMAD-1/5/9. BMP signaling agonist sb4 activates BMP4 target genes (inhibitors of DNA binding,?Id1?and?Id3) canonical BMP signaling[1].

Applications: Cancer-Kinase/protease

Formula: C14H10BrNOS

References: [1]Bradford STJ, et al. High-throughput screens for agonists of bone morphogenetic protein (BMP) signaling identify potent benzoxazole compounds.J Biol Chem. 2019 Mar 1;294(9):3125-3136.

CAS Number: 100874-08-6

Molecular Weight: 320.20

Compound Purity: 99.98

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: TGF-β Receptor

• SKU: MEXHY-124697-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-124697-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK