BMS-582949 (hydrochloride), CAS 912806-16-7

Product Description: BMS-582949 hydrochloride is an orally active and highly selective p38α MAPK inhibitor, with an IC50 of 13 nM. BMS-582949 hydrochloride displays a significantly improved pharmacokinetic profile and is effective in inflammatory disease[1].

Applications: COVID-19-immunoregulation

Formula: C22H27ClN6O2

References: [1]Liu C, et al. Discovery of 4-(5-(cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl-N-propylpyrrolo[1,2-f][1,2,4]triazine-6-carboxamide (BMS-582949), a clinical p38α MAP kinase inhibitor for the treatment of inflammatory diseases. J Med Chem. 2010 Sep 23;53(18):6629-39.

CAS Number: 912806-16-7

Molecular Weight: 442.94

Compound Purity: 98.90

Research Area: Inflammation/Immunology

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: Autophagy;p38 MAPK

• SKU: MEXHY-14305A-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-14305A-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK