BMS-599626 Hydrochloride, CAS 873837-23-1

Description: BMS-599626 Hydrochloride (AC480 Hydrochloride) is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50 =22, 32 and 190 nM, respectively) with potential antineoplastic activity. BMS-599626 Hydrochloride inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.

CAS Number: 873837-23-1

Formula: C27H28ClFN8O3

Molecular Weight: 567,01

References: Wong TW, et al. Preclinical antitumor activity of BMS-599626, a pan-HER kinase inhibitor that inhibits HER1/HER2 homodimer and heterodimer signaling. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):6186-93.

• SKU: TGMT5390-25mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T5390-25mg
• Package Unit: 25 mg
• Quantity Unit: STK