Product Description: BMS-962212 is a direct, reversible, selective factor XIa (FXIa) inhibitor . BMS-962212 is well tolerated, with fast onset of pharmacodynamic (PD) responses and rapid elimination. BMS-962212 increases exposure dependently in activated partial thromboplastin time, and decreases exposure dependently in FXI clotting activity[1].
Applications: Neuroscience-Neuromodulation
Formula: C32H28ClFN8O5
References: [1]Perera V, et al. First-in-human study to assess the safety, pharmacokinetics and pharmacodynamics of BMS-962212, a direct, reversible, small molecule factor XIa inhibitor in non-Japanese and Japanese healthy subjects. Br J Clin Pharmacol. 2018 May;84(5):876-887.
CAS Number: 1430114-34-3
Molecular Weight: 659.07
Compound Purity: 99.33
Research Area: Cardiovascular Disease
Solubility: DMSO : 250 mg/mL (ultrasonic)
Target: Factor Xa
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