Product Description: BMS-986278 is a potent and orally active lysophosphatidic acid receptor 1 (LPA1) antagonist, with Kbs of 6.9 nM and 4.0 nM for human and mouse LPA1, respectively. BMS-986278 can be used for the research of pulmonary fibrotic diseases[1].
Applications: Neuroscience-Neuromodulation
Formula: C22H31N5O5
References: [1]Cheng PTW, et, al. Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA1) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases. J Med Chem. 2021 Nov 11;64(21):15549-15581.
CAS Number: 2170126-74-4
Molecular Weight: 445.51
Compound Purity: 99.95
Research Area: Others
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: LPL Receptor