BNC375, CAS 1557240-80-8

Product Description: BNC375 is a potent, selective, and orally available type I positive allosteric modulator of α7 nAChRs with an EC50 of 1.9 μM. BNC375 exhibits good CNS-agent like properties and clinical candidate potential. [1].

Applications: Neuroscience-Neuromodulation

Formula: C19H23ClN2O3S

References: [1]Andrew J Harvey, et al. Discovery of BNC375, a Potent, Selective, and Orally Available Type I Positive Allosteric Modulator of α7 nAChRs. ACS Med Chem Lett. 2019 Mar 25;10(5):754-760.

CAS Number: 1557240-80-8

Molecular Weight: 394.92

Compound Purity: 99.62

Research Area: Neurological Disease

Solubility: DMSO : 83.33 mg/mL (ultrasonic)

Target: nAChR

• SKU: MEXHY-128575-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-128575-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK