Boceprevir, CAS 394730-60-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: (1R,2S,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[(2S)-2-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-3-azabicyclo[3.1.0]hexane-2-carboxamide

Purity: ≥98%

Formula Markup: C27H45N5O5

Formula Weight: 519.7

CAS Number: 394730-60-0

Notes: Boceprevir is an inhibitor of hepatitis C virus (HCV) non-structural protease 3/4A (NS3/4A; Ki = 14 nM for the HCV genotype 1b enzyme).{30614} Boceprevir inhibits HCV replication in Huh7 cells (EC50 = 200 nM).{36164} It also inhibits severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro; Ki = 1.8 µM) and reduces cytopathic effects of SARS-CoV-2 in Vero cells (EC50 = 1.31 µM).{58053} Formulations containing boceprevir have been used in the treatment of HCV.

• SKU: CAY18379-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 18379-5
• Package Unit: 5 mg
• Quantity Unit: STK