Borofalan, CAS 80994-59-8

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 4-(borono-10B)-L-phenylalanine

Purity: ≥95%

Formula Markup: C9H12[10B]NO4

Formula Weight: 208.2

CAS Number: 80994-59-8

Notes: Borofalan is a radiation sensitizer that contains 10B, a stable isotope of boron.{68610} It sensitizes B16/F10 melanoma cells to fast and thermal neutron radiation when used at a concentration of 50 µg/ml. Borofalan (300 mg/kg) selectively accumulates in sarcoma tissues over blood, muscle, skin, liver, and brain tissue in rats.{68611} In vivo, borofalan (803 mg/kg), in combination with radiation, increases mean survival time in an F98 rat glioma model.{68612} Formulations containing borofalan have been used in boron neutron capture therapy (BNCT) of unresectable, locally recurrent head and neck cancer.

• SKU: CAY38760-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 38760-5
• Package Unit: 5 mg
• Quantity Unit: STK